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Astrocytes and Microglia as Non-cell Autonomous Players in the Pathogenesis of ALS

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disorder that leads to a progressive muscle wasting and paralysis. The pathological phenotypes are featured by severe motor neuron death and glial activation in the lumbar spinal cord. Proposed ALS pathogenic mechanisms include g...

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Detalles Bibliográficos
Autores principales: Lee, Junghee, Hyeon, Seung Jae, Im, Hyeonjoo, Ryu, Hyun, Kim, Yunha, Ryu, Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Brain and Neural Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081469/
https://www.ncbi.nlm.nih.gov/pubmed/27790057
http://dx.doi.org/10.5607/en.2016.25.5.233