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Serelaxin Elicits Bronchodilation and Enhances β-Adrenoceptor-Mediated Airway Relaxation

Treatment with β-adrenoceptor agonists does not fully overcome the symptoms associated with severe asthma. Serelaxin elicits potent uterine and vascular relaxation via its cognate receptor, RXFP1, and nitric oxide (NO) signaling, and is being clinically evaluated for the treatment of acute heart fai...

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Detalles Bibliográficos
Autores principales: Lam, Maggie, Royce, Simon G., Donovan, Chantal, Jelinic, Maria, Parry, Laura J., Samuel, Chrishan S., Bourke, Jane E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081476/
https://www.ncbi.nlm.nih.gov/pubmed/27833558
http://dx.doi.org/10.3389/fphar.2016.00406