Performance Characterization and Validation of Saliva as an Alternative Specimen Source for Detecting Hereditary Breast Cancer Mutations by Next Generation Sequencing

Identification of pathogenic germline mutations by next generation sequencing is a widely accepted tool for predicting the risk of hereditary cancer development. Blood is the most common source of DNA for such tests. However, blood as a sample type has many drawbacks, including the invasive collecti...

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Detalles Bibliográficos
Autores principales: Meghnani, Varsha, Mohammed, Nadeem, Giauque, Christopher, Nahire, Rahul, David, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081504/
https://www.ncbi.nlm.nih.gov/pubmed/27818992
http://dx.doi.org/10.1155/2016/2059041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081504/
https://www.ncbi.nlm.nih.gov/pubmed/27818992
http://dx.doi.org/10.1155/2016/2059041

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