An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors

Human induced pluripotent stem cells (hiPSCs) provide a potential resource for regenerative medicine. To identify the signalling pathway(s) contributing to the development of functional β cells, we established a tracing model consisting of dual knock-in hiPSCs (INS-Venus/NGN3-mCherry) (hIveNry) expr...

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Detalles Bibliográficos
Autores principales: Yamashita-Sugahara, Yzumi, Matsumoto, Masahito, Ohtaka, Manami, Nishimura, Ken, Nakanishi, Mahito, Mitani, Kohnosuke, Okazaki, Yasushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081516/
https://www.ncbi.nlm.nih.gov/pubmed/27786288
http://dx.doi.org/10.1038/srep35908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081516/
https://www.ncbi.nlm.nih.gov/pubmed/27786288
http://dx.doi.org/10.1038/srep35908

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