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An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors

Human induced pluripotent stem cells (hiPSCs) provide a potential resource for regenerative medicine. To identify the signalling pathway(s) contributing to the development of functional β cells, we established a tracing model consisting of dual knock-in hiPSCs (INS-Venus/NGN3-mCherry) (hIveNry) expr...

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Detalles Bibliográficos
Autores principales:	Yamashita-Sugahara, Yzumi, Matsumoto, Masahito, Ohtaka, Manami, Nishimura, Ken, Nakanishi, Mahito, Mitani, Kohnosuke, Okazaki, Yasushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081516/ https://www.ncbi.nlm.nih.gov/pubmed/27786288 http://dx.doi.org/10.1038/srep35908

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