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Synthesis and biological evaluation of matrine derivatives containing benzo-α-pyrone structure as potent anti-lung cancer agents

Matrine, an active component of root extracts from Sophora flavescens Ait, is the main chemical ingredient of Fufang Kushen injection which was approved by Chinese FDA (CFDA) in 1995 as an anticancer drug to treat non-small cell lung cancer and liver cancer in combination with other anticancer drugs...

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Detalles Bibliográficos
Autores principales: Wu, Lichuan, Wang, Guizhen, Liu, Shuaibing, Wei, Jinrui, Zhang, Sen, Li, Ming, Zhou, Guangbiao, Wang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081519/
https://www.ncbi.nlm.nih.gov/pubmed/27786281
http://dx.doi.org/10.1038/srep35918