Hi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization

Combining genome-wide structural models with phenomenological data is at the forefront of efforts to understand the organizational principles regulating the human genome. Here, we use chromosome-chromosome contact data as knowledge-based constraints for large-scale three-dimensional models of the hu...

Descripción completa

Detalles Bibliográficos
Autores principales: Di Stefano, Marco, Paulsen, Jonas, Lien, Tonje G., Hovig, Eivind, Micheletti, Cristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081523/
https://www.ncbi.nlm.nih.gov/pubmed/27786255
http://dx.doi.org/10.1038/srep35985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081523/
https://www.ncbi.nlm.nih.gov/pubmed/27786255
http://dx.doi.org/10.1038/srep35985

Ejemplares similares