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Hi-C-constrained physical models of human chromosomes recover functionally-related properties of genome organization
Combining genome-wide structural models with phenomenological data is at the forefront of efforts to understand the organizational principles regulating the human genome. Here, we use chromosome-chromosome contact data as knowledge-based constraints for large-scale three-dimensional models of the hu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081523/ https://www.ncbi.nlm.nih.gov/pubmed/27786255 http://dx.doi.org/10.1038/srep35985 |