Simultaneous delivery of Paclitaxel and Bcl-2 siRNA via pH-Sensitive liposomal nanocarrier for the synergistic treatment of melanoma

pH-sensitive drug carriers that are sensitive to the acidic (pH = ~6.5) microenvironments of tumor tissues have been primarily used as effective drug/gene/siRNA/microRNA carriers for releasing their payloads to tumor cells/tissues. Resistance to various drugs has become a big hurdle in systemic chem...

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Detalles Bibliográficos
Autores principales: Reddy, Teegala Lakshminarayan, Garikapati, Koteswara Rao, Reddy, S. Gopal, Reddy, B. V. Subba, Yadav, J. S., Bhadra, Utpal, Bhadra, Manika Pal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081533/
https://www.ncbi.nlm.nih.gov/pubmed/27786239
http://dx.doi.org/10.1038/srep35223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081533/
https://www.ncbi.nlm.nih.gov/pubmed/27786239
http://dx.doi.org/10.1038/srep35223

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