Survival of mature T cells depends on signaling through HOIP

T cell development in the thymus is controlled by a multistep process. The NF-κB pathway regulates T cell development as well as T cell activation at multiple differentiation stages. The linear ubiquitin chain assembly complex (LUBAC) is composed of Sharpin, HOIL-1L and HOIP, and it is crucial for r...

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Detalles Bibliográficos
Autores principales: Okamura, Kazumi, Kitamura, Akiko, Sasaki, Yoshiteru, Chung, Doo Hyun, Kagami, Shoji, Iwai, Kazuhiro, Yasutomo, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081559/
https://www.ncbi.nlm.nih.gov/pubmed/27786304
http://dx.doi.org/10.1038/srep36135

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081559/
https://www.ncbi.nlm.nih.gov/pubmed/27786304
http://dx.doi.org/10.1038/srep36135

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