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Survival of mature T cells depends on signaling through HOIP

T cell development in the thymus is controlled by a multistep process. The NF-κB pathway regulates T cell development as well as T cell activation at multiple differentiation stages. The linear ubiquitin chain assembly complex (LUBAC) is composed of Sharpin, HOIL-1L and HOIP, and it is crucial for r...

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Detalles Bibliográficos
Autores principales:	Okamura, Kazumi, Kitamura, Akiko, Sasaki, Yoshiteru, Chung, Doo Hyun, Kagami, Shoji, Iwai, Kazuhiro, Yasutomo, Koji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081559/ https://www.ncbi.nlm.nih.gov/pubmed/27786304 http://dx.doi.org/10.1038/srep36135

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