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C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing

BACKGROUND: Recent studies were able to demonstrate involvement of the complement cascade in bone biology. Further studies analyzed the role of complement in traumatic injuries and demonstrated negative effects after excessive systemic activation of the inflammatory response with early abrogation of...

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Detalles Bibliográficos
Autores principales: Ehrnthaller, Christian, Huber-Lang, Markus, Kovtun, Anna, Rapp, Anna Elise, Kemmler, Julia, Gebhard, Florian, Ignatius, Anita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081665/
https://www.ncbi.nlm.nih.gov/pubmed/27784330
http://dx.doi.org/10.1186/s40001-016-0236-7