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C5aR inhibition in the early inflammatory phase does not affect bone regeneration in a model of uneventful fracture healing
BACKGROUND: Recent studies were able to demonstrate involvement of the complement cascade in bone biology. Further studies analyzed the role of complement in traumatic injuries and demonstrated negative effects after excessive systemic activation of the inflammatory response with early abrogation of...
Autores principales: | Ehrnthaller, Christian, Huber-Lang, Markus, Kovtun, Anna, Rapp, Anna Elise, Kemmler, Julia, Gebhard, Florian, Ignatius, Anita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081665/ https://www.ncbi.nlm.nih.gov/pubmed/27784330 http://dx.doi.org/10.1186/s40001-016-0236-7 |
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