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Differential effects of altered patterns of movement and strain on joint cell behaviour and skeletal morphogenesis

OBJECTIVE: There is increasing evidence that joint shape is a potent predictor of osteoarthritis (OA) risk; yet the cellular events underpinning joint morphogenesis remain unclear. We sought to develop a genetically tractable animal model to study the events controlling joint morphogenesis. DESIGN:...

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Detalles Bibliográficos
Autores principales: Brunt, L.H., Skinner, R.E.H., Roddy, K.A., Araujo, N.M., Rayfield, E.J., Hammond, C.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: W.B. Saunders For The Osteoarthritis Research Society 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081689/
https://www.ncbi.nlm.nih.gov/pubmed/27374878
http://dx.doi.org/10.1016/j.joca.2016.06.015