Very large treatment effects in randomised trials as an empirical marker to indicate whether subsequent trials are necessary: meta-epidemiological assessment

Objective To examine whether a very large effect (VLE; defined as a relative risk of ≤0.2 or ≥5) in a randomised trial could be an empirical marker that subsequent trials are unnecessary. Design Meta-epidemiological assessment of existing published data on randomised trials. Data sources Cochrane Da...

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Detalles Bibliográficos
Autores principales: Nagendran, Myura, Pereira, Tiago V, Kiew, Grace, Altman, Douglas G, Maruthappu, Mahiben, Ioannidis, John P A, McCulloch, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081692/
https://www.ncbi.nlm.nih.gov/pubmed/27789483
http://dx.doi.org/10.1136/bmj.i5432

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5081692/
https://www.ncbi.nlm.nih.gov/pubmed/27789483
http://dx.doi.org/10.1136/bmj.i5432

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