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P‐glycoprotein overexpression in bone marrow–derived multipotent stromal cells decreases the risk of steroid‐induced osteonecrosis in the femoral head

P‐glycoprotein (P‐gp) plays a role in steroid‐induced osteonecrosis of the femoral head (ONFH), but the underlying mechanism remains unknown. We hypothesized that P‐gp overexpression can prevent ONFH by regulating bone marrow–derived multipotent stromal cell (BMSC) adipogenesis and osteogenesis. BMS...

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Detalles Bibliográficos
Autores principales: Han, Ning, Li, Zengchun, Cai, Zhengdong, Yan, Zuoqin, Hua, Yingqi, Xu, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082398/
https://www.ncbi.nlm.nih.gov/pubmed/27396977
http://dx.doi.org/10.1111/jcmm.12917