Aerobic exercise training rescues cardiac protein quality control and blunts endoplasmic reticulum stress in heart failure rats

Cardiac endoplasmic reticulum (ER) stress through accumulation of misfolded proteins plays a pivotal role in cardiovascular diseases. In an attempt to reestablish ER homoeostasis, the unfolded protein response (UPR) is activated. However, if ER stress persists, sustained UPR activation leads to apop...

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Detalles Bibliográficos
Autores principales: Bozi, Luiz H. M., Jannig, Paulo R., Rolim, Natale, Voltarelli, Vanessa A., Dourado, Paulo M. M., Wisløff, Ulrik, Brum, Patricia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082404/
https://www.ncbi.nlm.nih.gov/pubmed/27305869
http://dx.doi.org/10.1111/jcmm.12894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082404/
https://www.ncbi.nlm.nih.gov/pubmed/27305869
http://dx.doi.org/10.1111/jcmm.12894

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