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Aerobic exercise training rescues cardiac protein quality control and blunts endoplasmic reticulum stress in heart failure rats
Cardiac endoplasmic reticulum (ER) stress through accumulation of misfolded proteins plays a pivotal role in cardiovascular diseases. In an attempt to reestablish ER homoeostasis, the unfolded protein response (UPR) is activated. However, if ER stress persists, sustained UPR activation leads to apop...
Autores principales: | Bozi, Luiz H. M., Jannig, Paulo R., Rolim, Natale, Voltarelli, Vanessa A., Dourado, Paulo M. M., Wisløff, Ulrik, Brum, Patricia C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082404/ https://www.ncbi.nlm.nih.gov/pubmed/27305869 http://dx.doi.org/10.1111/jcmm.12894 |
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