Hypoxanthine induces cholesterol accumulation and incites atherosclerosis in apolipoprotein E‐deficient mice and cells

Reactive oxygen species (ROS) generation during purine metabolism is associated with xanthine oxidase and uric acid. However, the direct effect of hypoxanthine on ROS generation and atherosclerosis has not been evaluated. Smoking and heavy drinking are associated with elevated levels of hypoxanthine...

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Detalles Bibliográficos
Autores principales: Ryu, Hye‐Myung, Kim, You‐Jin, Oh, Eun‐Joo, Oh, Se‐Hyun, Choi, Ji‐Young, Cho, Jang‐Hee, Kim, Chan‐Duck, Park, Sun‐Hee, Kim, Yong‐Lim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082407/
https://www.ncbi.nlm.nih.gov/pubmed/27396856
http://dx.doi.org/10.1111/jcmm.12916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082407/
https://www.ncbi.nlm.nih.gov/pubmed/27396856
http://dx.doi.org/10.1111/jcmm.12916

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