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Economical and scalable synthesis of 6-amino-2-cyanobenzothiazole

2-Cyanobenzothiazoles (CBTs) are useful building blocks for: 1) luciferin derivatives for bioluminescent imaging; and 2) handles for bioorthogonal ligations. A particularly versatile CBT is 6-amino-2-cyanobenzothiazole (ACBT), which has an amine handle for straight-forward derivatisation. Here we pr...

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Detalles Bibliográficos
Autores principales: Hauser, Jacob R, Beard, Hester A, Bayana, Mary E, Jolley, Katherine E, Warriner, Stuart L, Bon, Robin S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082452/
https://www.ncbi.nlm.nih.gov/pubmed/27829906
http://dx.doi.org/10.3762/bjoc.12.189