Practical synthetic strategies towards lipophilic 6-iodotetrahydroquinolines and -dihydroquinolines

The synthesis of novel tetrahydroquinolines (THQ) and dihydroquinolines (DHQ) are reported using three practical, scalable synthetic approaches to access highly lipophilic analogues bearing a 6-iodo substituent, each with a different means of cyclisation. A versatile and stable quinolin-2-one interm...

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Detalles Bibliográficos
Autores principales: Chisholm, David R, Zhou, Garr-Layy, Pohl, Ehmke, Valentine, Roy, Whiting, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082455/
https://www.ncbi.nlm.nih.gov/pubmed/27829891
http://dx.doi.org/10.3762/bjoc.12.174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082455/
https://www.ncbi.nlm.nih.gov/pubmed/27829891
http://dx.doi.org/10.3762/bjoc.12.174

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