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Practical synthetic strategies towards lipophilic 6-iodotetrahydroquinolines and -dihydroquinolines
The synthesis of novel tetrahydroquinolines (THQ) and dihydroquinolines (DHQ) are reported using three practical, scalable synthetic approaches to access highly lipophilic analogues bearing a 6-iodo substituent, each with a different means of cyclisation. A versatile and stable quinolin-2-one interm...
Autores principales: | Chisholm, David R, Zhou, Garr-Layy, Pohl, Ehmke, Valentine, Roy, Whiting, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082455/ https://www.ncbi.nlm.nih.gov/pubmed/27829891 http://dx.doi.org/10.3762/bjoc.12.174 |
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