Diastereoselective synthesis of 3,4-dihydro-2H-pyran-4-carboxamides through an unusual regiospecific quasi-hydrolysis of a cyano group

An efficient diastereoselective approach for the synthesis of functionalized 3,4-dihydro-2H-pyran-4-carboxamides with variable frame was developed based on the reaction of available 4-oxoalkane-1,1,2,2-tetracarbonitriles (adducts of TCNE and ketones) with aldehydes in an acidic media. An unusual pro...

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Detalles Bibliográficos
Autores principales: Ievlev, Mikhail Yu, Ershov, Oleg V, Belikov, Mikhail Yu, Milovidova, Angelina G, Tafeenko, Viktor A, Nasakin, Oleg E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082461/
https://www.ncbi.nlm.nih.gov/pubmed/27829915
http://dx.doi.org/10.3762/bjoc.12.198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082461/
https://www.ncbi.nlm.nih.gov/pubmed/27829915
http://dx.doi.org/10.3762/bjoc.12.198

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