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Excited States of Nucleic Acids Probed by Proton Relaxation Dispersion NMR Spectroscopy

In this work an improved stable isotope labeling protocol for nucleic acids is introduced. The novel building blocks eliminate/minimize homonuclear (13)C and (1)H scalar couplings thus allowing proton relaxation dispersion (RD) experiments to report accurately on the chemical exchange of nucleic aci...

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Detalles Bibliográficos
Autores principales: Juen, Michael Andreas, Wunderlich, Christoph Hermann, Nußbaumer, Felix, Tollinger, Martin, Kontaxis, Georg, Konrat, Robert, Hansen, D. Flemming, Kreutz, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082494/
https://www.ncbi.nlm.nih.gov/pubmed/27533469
http://dx.doi.org/10.1002/anie.201605870