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Excited States of Nucleic Acids Probed by Proton Relaxation Dispersion NMR Spectroscopy
In this work an improved stable isotope labeling protocol for nucleic acids is introduced. The novel building blocks eliminate/minimize homonuclear (13)C and (1)H scalar couplings thus allowing proton relaxation dispersion (RD) experiments to report accurately on the chemical exchange of nucleic aci...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082494/ https://www.ncbi.nlm.nih.gov/pubmed/27533469 http://dx.doi.org/10.1002/anie.201605870 |