Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists

It has now been demonstrated that the μ, δ(1), δ(2), and κ(1) opioid receptor (OR) agonists represent the most promising group of opioids for the creation of drugs enhancing cardiac tolerance to the detrimental effects of ischemia/reperfusion (I/R). Opioids are able to prevent necrosis and apoptosis...

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Detalles Bibliográficos
Autores principales: Maslov, Leonid N, Khaliulin, Igor, Oeltgen, Peter R., Naryzhnaya, Natalia V., Pei, Jian‐Ming, Brown, Stephen A., Lishmanov, Yury B., Downey, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082499/
https://www.ncbi.nlm.nih.gov/pubmed/27197922
http://dx.doi.org/10.1002/med.21395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082499/
https://www.ncbi.nlm.nih.gov/pubmed/27197922
http://dx.doi.org/10.1002/med.21395

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