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Prospects for Creation of Cardioprotective and Antiarrhythmic Drugs Based on Opioid Receptor Agonists
It has now been demonstrated that the μ, δ(1), δ(2), and κ(1) opioid receptor (OR) agonists represent the most promising group of opioids for the creation of drugs enhancing cardiac tolerance to the detrimental effects of ischemia/reperfusion (I/R). Opioids are able to prevent necrosis and apoptosis...
Autores principales: | Maslov, Leonid N, Khaliulin, Igor, Oeltgen, Peter R., Naryzhnaya, Natalia V., Pei, Jian‐Ming, Brown, Stephen A., Lishmanov, Yury B., Downey, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082499/ https://www.ncbi.nlm.nih.gov/pubmed/27197922 http://dx.doi.org/10.1002/med.21395 |
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