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IL‐33 delivery induces serous cavity macrophage proliferation independent of interleukin‐4 receptor alpha

IL‐33 plays an important role in the initiation of type‐2 immune responses, as well as the enhancement of type 2 effector functions. Engagement of the IL‐33 receptor on macrophages facilitates polarization to an alternative activation state by amplifying IL‐4 and IL‐13 signaling to IL‐4Rα. IL‐4 and...

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Detalles Bibliográficos
Autores principales: Jackson‐Jones, Lucy H., Rückerl, Dominik, Svedberg, Freya, Duncan, Sheelagh, Maizels, Rick M., Sutherland, Tara E., Jenkins, Stephen J., McSorley, Henry J., Bénézech, Cécile, MacDonald, Andrew S., Allen, Judith E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082546/
https://www.ncbi.nlm.nih.gov/pubmed/27592711
http://dx.doi.org/10.1002/eji.201646442