Loss of strumpellin in the melanocytic lineage impairs the WASH Complex but does not affect coat colour

The five‐subunit WASH complex generates actin networks that participate in endocytic trafficking, migration and invasion in various cell types. Loss of one of the two subunits WASH or strumpellin in mice is lethal, but little is known about their role in mammals in vivo. We explored the role of stru...

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Detalles Bibliográficos
Autores principales: Tyrrell, Benjamin J., Woodham, Emma F., Spence, Heather J., Strathdee, Douglas, Insall, Robert H., Machesky, Laura M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082549/
https://www.ncbi.nlm.nih.gov/pubmed/27390154
http://dx.doi.org/10.1111/pcmr.12506

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082549/
https://www.ncbi.nlm.nih.gov/pubmed/27390154
http://dx.doi.org/10.1111/pcmr.12506

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