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Synthesis and evaluation of an (18)F‐labeled derivative of F3 for targeting surface‐expressed nucleolin in cancer and tumor endothelial cells

The surface overexpression of nucleolin provides an anchor for the specific attachment of biomolecules to cancer and angiogenic endothelial cells. The peptide F3 is a high‐affinity ligand of the nucleolin receptor (NR) that has been investigated as a carrier to deliver biologically active molecules...

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Detalles Bibliográficos
Autores principales: Lam, Phoebe Y.H., Hillyar, Christopher R.T., Able, Sarah, Vallis, Katherine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082555/
https://www.ncbi.nlm.nih.gov/pubmed/27594091
http://dx.doi.org/10.1002/jlcr.3439