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Synthesis and evaluation of an (18)F‐labeled derivative of F3 for targeting surface‐expressed nucleolin in cancer and tumor endothelial cells
The surface overexpression of nucleolin provides an anchor for the specific attachment of biomolecules to cancer and angiogenic endothelial cells. The peptide F3 is a high‐affinity ligand of the nucleolin receptor (NR) that has been investigated as a carrier to deliver biologically active molecules...
Autores principales: | Lam, Phoebe Y.H., Hillyar, Christopher R.T., Able, Sarah, Vallis, Katherine A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082555/ https://www.ncbi.nlm.nih.gov/pubmed/27594091 http://dx.doi.org/10.1002/jlcr.3439 |
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