A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug‐induced liver injury and postinjury inflammation in mice

Acetaminophen (APAP) overdoses are of major clinical concern. Growing evidence underlines a pathogenic contribution of sterile postinjury inflammation in APAP‐induced acute liver injury (APAP‐ALI) and justifies development of anti‐inflammatory therapies with therapeutic efficacy beyond the therapeut...

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Detalles Bibliográficos
Autores principales: Lundbäck, Peter, Lea, Jonathan D., Sowinska, Agnieszka, Ottosson, Lars, Fürst, Camilla Melin, Steen, Johanna, Aulin, Cecilia, Clarke, Joanna I., Kipar, Anja, Klevenvall, Lena, Yang, Huan, Palmblad, Karin, Park, B. Kevin, Tracey, Kevin J., Blom, Anna M., Andersson, Ulf, Antoine, Daniel J., Erlandsson Harris, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Liver Injury/Regeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082559/
https://www.ncbi.nlm.nih.gov/pubmed/27474782
http://dx.doi.org/10.1002/hep.28736

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082559/
https://www.ncbi.nlm.nih.gov/pubmed/27474782
http://dx.doi.org/10.1002/hep.28736

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