Cargando…

Bias due to participant overlap in two‐sample Mendelian randomization

Mendelian randomization analyses are often performed using summarized data. The causal estimate from a one‐sample analysis (in which data are taken from a single data source) with weak instrumental variables is biased in the direction of the observational association between the risk factor and outc...

Descripción completa

Detalles Bibliográficos
Autores principales: Burgess, Stephen, Davies, Neil M., Thompson, Simon G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082560/
https://www.ncbi.nlm.nih.gov/pubmed/27625185
http://dx.doi.org/10.1002/gepi.21998