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Bias due to participant overlap in two‐sample Mendelian randomization
Mendelian randomization analyses are often performed using summarized data. The causal estimate from a one‐sample analysis (in which data are taken from a single data source) with weak instrumental variables is biased in the direction of the observational association between the risk factor and outc...
Autores principales: | Burgess, Stephen, Davies, Neil M., Thompson, Simon G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082560/ https://www.ncbi.nlm.nih.gov/pubmed/27625185 http://dx.doi.org/10.1002/gepi.21998 |
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