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IRBP deficiency permits precocious ocular development and myopia

PURPOSE: Interphotoreceptor retinoid-binding protein (IRBP) is abundant in the subretinal space and binds retinoids and lipophilic molecules. The expression of IRBP begins precociously early in mouse eye development. IRBP-deficient (KO) mice show less cell death in the inner retinal layers of the re...

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Detalles Bibliográficos
Autores principales: Markand, Shanu, Baskin, Natecia L., Chakraborty, Ranjay, Landis, Erica, Wetzstein, Sara A., Donaldson, Kevin J., Priyadarshani, Priyanka, Alderson, Shannon E., Sidhu, Curran S., Boatright, Jeffrey H., Iuvone, P. Michael, Pardue, Machelle T., Nickerson, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082647/
https://www.ncbi.nlm.nih.gov/pubmed/27829784