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IRBP deficiency permits precocious ocular development and myopia
PURPOSE: Interphotoreceptor retinoid-binding protein (IRBP) is abundant in the subretinal space and binds retinoids and lipophilic molecules. The expression of IRBP begins precociously early in mouse eye development. IRBP-deficient (KO) mice show less cell death in the inner retinal layers of the re...
Autores principales: | Markand, Shanu, Baskin, Natecia L., Chakraborty, Ranjay, Landis, Erica, Wetzstein, Sara A., Donaldson, Kevin J., Priyadarshani, Priyanka, Alderson, Shannon E., Sidhu, Curran S., Boatright, Jeffrey H., Iuvone, P. Michael, Pardue, Machelle T., Nickerson, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Vision
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082647/ https://www.ncbi.nlm.nih.gov/pubmed/27829784 |
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