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Efficacy of Intrathecal Morphine in a Model of Surgical Pain in Rats

Concerns over interactions between analgesics and experimental outcomes are a major reason for withholding opioids from rats undergoing surgical procedures. Only a fraction of morphine injected intravenously reaches receptors responsible for analgesia in the central nervous system. Intrathecal admin...

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Detalles Bibliográficos
Autores principales: Thomas, Aurelie, Miller, Amy, Roughan, Johnny, Malik, Aneesa, Haylor, Katherine, Sandersen, Charlotte, Flecknell, Paul, Leach, Matthew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082666/
https://www.ncbi.nlm.nih.gov/pubmed/27783629
http://dx.doi.org/10.1371/journal.pone.0163909