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Efficacy of Intrathecal Morphine in a Model of Surgical Pain in Rats
Concerns over interactions between analgesics and experimental outcomes are a major reason for withholding opioids from rats undergoing surgical procedures. Only a fraction of morphine injected intravenously reaches receptors responsible for analgesia in the central nervous system. Intrathecal admin...
Autores principales: | Thomas, Aurelie, Miller, Amy, Roughan, Johnny, Malik, Aneesa, Haylor, Katherine, Sandersen, Charlotte, Flecknell, Paul, Leach, Matthew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082666/ https://www.ncbi.nlm.nih.gov/pubmed/27783629 http://dx.doi.org/10.1371/journal.pone.0163909 |
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