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Chiral ammonium betaine-catalyzed asymmetric Mannich-type reaction of oxindoles
A highly diastereo- and enantioselective Mannich-type reaction of 3-aryloxindoles with N-Boc aldimines was achieved under the catalysis of axially chiral ammonium betaines. This catalytic method provides a new tool for the construction of consecutive quaternary and tertiary stereogenic carbon center...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082719/ https://www.ncbi.nlm.nih.gov/pubmed/27829916 http://dx.doi.org/10.3762/bjoc.12.199 |