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Chiral ammonium betaine-catalyzed asymmetric Mannich-type reaction of oxindoles

A highly diastereo- and enantioselective Mannich-type reaction of 3-aryloxindoles with N-Boc aldimines was achieved under the catalysis of axially chiral ammonium betaines. This catalytic method provides a new tool for the construction of consecutive quaternary and tertiary stereogenic carbon center...

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Detalles Bibliográficos
Autores principales:	Torii, Masahiro, Kato, Kohsuke, Uraguchi, Daisuke, Ooi, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2016
Materias:	Letter
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082719/ https://www.ncbi.nlm.nih.gov/pubmed/27829916 http://dx.doi.org/10.3762/bjoc.12.199

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