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Application of heterocyclic aldehydes as components in Ugi–Smiles couplings

Efficient one-pot Ugi–Smiles couplings are reported for the use of furyl-substituted aldehyde components. In the presence of these heterocyclic aldehydes, reactions tolerated variations in amine components and led to either isolated N-arylamide Ugi–Smiles adducts or N-arylepoxyisoindolines, products...

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Detalles Bibliográficos
Autores principales: Mason, Katelynn M, Meyers, Michael S, Fox, Abbie M, Luesse, Sarah B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082724/
https://www.ncbi.nlm.nih.gov/pubmed/27829908
http://dx.doi.org/10.3762/bjoc.12.191