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Light-sheet Bayesian microscopy enables deep-cell super-resolution imaging of heterochromatin in live human embryonic stem cells

BACKGROUND: Heterochromatin in the nucleus of human embryonic cells plays an important role in the epigenetic regulation of gene expression. The architecture of heterochromatin and its dynamic organization remain elusive because of the lack of fast and high-resolution deep-cell imaging tools. We ena...

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Detalles Bibliográficos
Autores principales: Hu, Ying S, Zhu, Quan, Elkins, Keri, Tse, Kevin, Li, Yu, Fitzpatrick, James A J, Verma, Inder M, Cang, Hu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082751/
https://www.ncbi.nlm.nih.gov/pubmed/27795878
http://dx.doi.org/10.1186/2192-2853-2-7