Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma

Protein tyrosine phosphatase 1B (PTP1B) is known to promote the pathogenesis of diabetes and obesity by negatively regulating insulin and leptin pathways, but its role associated with colon carcinogenesis is still under debate. In this study, we demonstrated the oncogenic role of PTP1B in promoting...

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Detalles Bibliográficos
Autores principales: Teng, Hao-Wei, Hung, Man-Hsin, Chen, Li-Ju, Chang, Mao-Ju, Hsieh, Feng-Shu, Tsai, Ming-Hsien, Huang, Jui-Wen, Lin, Chih-Lung, Tseng, Hsiang-Wen, Kuo, Zong-Keng, Jiang, Jeng-Kai, Yang, Shung-Haur, Shiau, Chung-Wai, Chen, Kuen-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082755/
https://www.ncbi.nlm.nih.gov/pubmed/27752061
http://dx.doi.org/10.1038/srep35308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082755/
https://www.ncbi.nlm.nih.gov/pubmed/27752061
http://dx.doi.org/10.1038/srep35308

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