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Protein tyrosine phosphatase 1B targets PITX1/p120RasGAP thus showing therapeutic potential in colorectal carcinoma
Protein tyrosine phosphatase 1B (PTP1B) is known to promote the pathogenesis of diabetes and obesity by negatively regulating insulin and leptin pathways, but its role associated with colon carcinogenesis is still under debate. In this study, we demonstrated the oncogenic role of PTP1B in promoting...
Autores principales: | Teng, Hao-Wei, Hung, Man-Hsin, Chen, Li-Ju, Chang, Mao-Ju, Hsieh, Feng-Shu, Tsai, Ming-Hsien, Huang, Jui-Wen, Lin, Chih-Lung, Tseng, Hsiang-Wen, Kuo, Zong-Keng, Jiang, Jeng-Kai, Yang, Shung-Haur, Shiau, Chung-Wai, Chen, Kuen-Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082755/ https://www.ncbi.nlm.nih.gov/pubmed/27752061 http://dx.doi.org/10.1038/srep35308 |
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