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TRAF3 deficiency promotes metabolic reprogramming in B cells

The adaptor protein TNF receptor-associated factor 3 (TRAF3) is a critical regulator of B lymphocyte survival. B cell-specific TRAF3 deficiency results in enhanced viability and is associated with development of lymphoma and multiple myeloma. We show that TRAF3 deficiency led to induction of two pro...

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Detalles Bibliográficos
Autores principales: Mambetsariev, Nurbek, Lin, Wai W., Wallis, Alicia M., Stunz, Laura L., Bishop, Gail A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082756/
https://www.ncbi.nlm.nih.gov/pubmed/27752131
http://dx.doi.org/10.1038/srep35349