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TRAF3 deficiency promotes metabolic reprogramming in B cells
The adaptor protein TNF receptor-associated factor 3 (TRAF3) is a critical regulator of B lymphocyte survival. B cell-specific TRAF3 deficiency results in enhanced viability and is associated with development of lymphoma and multiple myeloma. We show that TRAF3 deficiency led to induction of two pro...
Autores principales: | Mambetsariev, Nurbek, Lin, Wai W., Wallis, Alicia M., Stunz, Laura L., Bishop, Gail A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082756/ https://www.ncbi.nlm.nih.gov/pubmed/27752131 http://dx.doi.org/10.1038/srep35349 |
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