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Myc overexpression enhances of epicardial contribution to the developing heart and promotes extensive expansion of the cardiomyocyte population

Myc is an essential regulator of cell growth and proliferation. Myc overexpression promotes the homeostatic expansion of cardiomyocyte populations by cell competition, however whether this applies to other cardiac lineages remains unknown. The epicardium contributes signals and cells to the developi...

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Detalles Bibliográficos
Autores principales: Villa del Campo, Cristina, Lioux, Ghislaine, Carmona, Rita, Sierra, Rocío, Muñoz-Chápuli, Ramón, Clavería, Cristina, Torres, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082763/
https://www.ncbi.nlm.nih.gov/pubmed/27752085
http://dx.doi.org/10.1038/srep35366