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A spatial covariance (123)I-5IA-85380 SPECT study of α4β2 nicotinic receptors in Alzheimer's disease

Alzheimer's disease (AD) is characterized by widespread degeneration of cholinergic neurons, particularly in the basal forebrain. However, the pattern of these deficits and relationship with known brain networks is unknown. In this study, we sought to clarify this and used (123)I-5-iodo-3-[2(S)...

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Detalles Bibliográficos
Autores principales: Colloby, Sean J., Field, Robert H., Wyper, David J., O'Brien, John T., Taylor, John-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082764/
https://www.ncbi.nlm.nih.gov/pubmed/27565302
http://dx.doi.org/10.1016/j.neurobiolaging.2016.07.017