Sphingomyelin Synthase 1 Is Essential for Male Fertility in Mice

Sphingolipids and the derived gangliosides have critical functions in spermatogenesis, thus mutations in genes involved in sphingolipid biogenesis are often associated with male infertility. We have generated a transgenic mouse line carrying an insertion in the sphingomyelin synthase gene Sms1, the...

Descripción completa

Detalles Bibliográficos
Autores principales: Wittmann, Anke, Grimm, Marcus O. W., Scherthan, Harry, Horsch, Marion, Beckers, Johannes, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabě de Angelis, Martin, Ford, Steven J., Burton, Neal C., Razansky, Daniel, Trümbach, Dietrich, Aichler, Michaela, Walch, Axel Karl, Calzada-Wack, Julia, Neff, Frauke, Wurst, Wolfgang, Hartmann, Tobias, Floss, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082796/
https://www.ncbi.nlm.nih.gov/pubmed/27788151
http://dx.doi.org/10.1371/journal.pone.0164298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082796/
https://www.ncbi.nlm.nih.gov/pubmed/27788151
http://dx.doi.org/10.1371/journal.pone.0164298

Ejemplares similares