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Mechanical Flexibility Reduces the Foreign Body Response to Long-Term Implanted Microelectrodes in Rabbit Cortex

Micromotion between the brain and implanted electrodes is a major contributor to the failure of invasive microelectrodes. Movements of the electrode tip cause recording instabilities while spike amplitudes decline over the weeks/months post-implantation due to glial cell activation caused by sustain...

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Detalles Bibliográficos
Autores principales: Sohal, Harbaljit S., Clowry, Gavin J., Jackson, Andrew, O’Neill, Anthony, Baker, Stuart N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082854/
https://www.ncbi.nlm.nih.gov/pubmed/27788240
http://dx.doi.org/10.1371/journal.pone.0165606