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Mechanical Flexibility Reduces the Foreign Body Response to Long-Term Implanted Microelectrodes in Rabbit Cortex
Micromotion between the brain and implanted electrodes is a major contributor to the failure of invasive microelectrodes. Movements of the electrode tip cause recording instabilities while spike amplitudes decline over the weeks/months post-implantation due to glial cell activation caused by sustain...
Autores principales: | Sohal, Harbaljit S., Clowry, Gavin J., Jackson, Andrew, O’Neill, Anthony, Baker, Stuart N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5082854/ https://www.ncbi.nlm.nih.gov/pubmed/27788240 http://dx.doi.org/10.1371/journal.pone.0165606 |
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